SCHEMBL1765932

SCHEMBL1765932

C=CCOC(=O)N(S)S.[Zn]

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
SNCA P37840 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL461759 0.98
SCHEMBL1901077 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL1766021 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL2522350 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL1906085 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL9498811 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL1766029 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL11666658 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL1766016 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1
SCHEMBL7570864 0.95 TSHR (0.41) TSHRCYP3A4MAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752426-B Composite calcium sulfonate-based lubricating grease and preparation method thereof 中国石油天然气股份有限公司 2023-12-22 CN claimed
CN-114752426-A Composite calcium sulfonate-based lubricating grease and preparation method thereof 中国石油天然气股份有限公司 2022-07-15 CN claimed
EP-2504099-B1 HYDROPROCESSING BULK CATALYST, IT'S USE AND METHODS OF MAKING THEREOF CHEVRON USA INC (US) 2021-08-11 EP claimed
CN-112063174-A Heat-resistant aramid fiber synchronous belt and preparation method thereof 宁波伏龙同步带有限公司 2020-12-11 CN claimed
US-8420565-B2 Hydroprocessing bulk catalyst and methods of making thereof CHEVRON U.S.A. INC. (US) 2013-04-16 US claimed
EP-2504099-A2 HYDROPROCESSING BULK CATALYST AND METHODS OF MAKING THEREOF Chevron U.S.A. Inc. (US) 2012-10-03 EP claimed
WO-2011066150-A2 HYDROPROCESSING BULK CATALYST AND METHODS OF MAKING THEREOF CHEVRON U.S.A. INC. (US) 2011-06-03 WO claimed
US-20110124496-A1 Hydroprocessing Bulk Catalyst and Methods of Making Thereof CHEVRON U.S.A. INC. 2011-05-26 US claimed
EP-0716678-A1 AUTOMOTIVE WHITE OIL-BASED LUBRICANT COMPOSITION ESSO SOCIETE ANONYME FRANCAISE (FR) 1996-06-19 EP claimed
WO-1995006701-A1 AUTOMOTIVE WHITE OIL-BASED LUBRICANT COMPOSITION ESSO SOCIETE ANONYME FRANÇAISE (FR) 1995-03-09 WO claimed
EP-0171926-B1 DYNAMICALLY CURED THERMOPLASTIC OLEFIN POLYMERS ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1993-03-31 EP claimed
US-4845145-A GASKETS EXXON RESEARCH & ENGINEERING COMPANY (US) 1989-07-04 US claimed
US-4607074-A BLENDED WITH ONE VULCANIZED AND AT LEAST ONE UNVULACNIZED RUBBER EXXON RESEARCH & ENGINEERING CO. (US) 1986-08-19 US claimed
EP-0171926-A2 Dynamically cured thermoplastic olefin polymers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1986-02-19 EP claimed
CN-114752426-A Composite calcium sulfonate-based lubricating grease and preparation method thereof 中国石油天然气股份有限公司 2022-07-15 CN disclosed
EP-2504099-B1 HYDROPROCESSING BULK CATALYST, IT'S USE AND METHODS OF MAKING THEREOF CHEVRON USA INC (US) 2021-08-11 EP disclosed
CN-112063174-A Heat-resistant aramid fiber synchronous belt and preparation method thereof 宁波伏龙同步带有限公司 2020-12-11 CN disclosed
US-4861635-A Pressure-sensitive adhesive closure for disposable diaper MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-29 US disclosed
EP-0316601-A2 Pressure-sensitive adhesive closure for disposable diaper MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-24 EP disclosed
EP-0306232-A2 Pressure-sensitive adhesive composition, tape and diaper closure system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed