Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661314 | 0.95 | ALK (0.40) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17547175 | 0.90 | SIRT2 (0.48) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17547221 | 0.89 | SIRT2 (0.47) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL18767302 | 0.89 | SIRT2 (0.47) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17661463 | 0.89 | SIRT2 (0.49) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17454545 | 0.88 | SIRT2 (0.48) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17547297 | 0.86 | SIRT2 (0.47) | SIRT2SIRT1AKR1C3ALKSYK | |
| SCHEMBL17463827 | 0.86 | ALK (0.42) | SIRT2SIRT1AKR1C3ALKMEN1 | |
| SCHEMBL17547202 | 0.86 | ALK (0.42) | SIRT2SIRT1AKR1C3ALKMEN1 | |
| SCHEMBL17779640 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1AKR1C3ALKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016052835-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-04-07 | — | — | WO | disclosed |