⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890015 | 0.79 | — | — | |
| SCHEMBL268557 | 0.79 | — | — | |
| SCHEMBL128903 | 0.79 | — | — | |
| SCHEMBL28436034 | 0.77 | BLM (0.41) | — | |
| SCHEMBL7019853 | 0.75 | — | — | |
| SCHEMBL19004774 | 0.75 | CA1 (0.52) | — | |
| SCHEMBL3286382 | 0.75 | CA1 (0.52) | — | |
| SCHEMBL29008724 | 0.75 | HPGD (0.30) | — | |
| SCHEMBL19754830 | 0.75 | CYP1A2 (0.37) | — | |
| SCHEMBL25796677 | 0.75 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096175-A1 | Compounds and Methods for Altering Lifespan of Eukaryotic Organisms | SOUTHERN RESEARCH INSTITUTE (US) | 2013-04-18 | — | — | US | claimed |
| EP-2501229-A1 | COMPOUNDS AND METHODS FOR ALTERING LIFESPAN OF EUKARYOTIC ORGANISMS | University Of Rochester (US) | 2012-09-26 | — | — | EP | claimed |
| WO-2011062964-A1 | COMPOUNDS AND METHODS FOR ALTERING LIFESPAN OF EUKARYOTIC ORGANISMS | UNIVERSITY OF ROCHESTER (US) | 2011-05-26 | — | — | WO | claimed |
| US-8846747-B2 | Compounds and methods for altering lifespan of eukaryotic organisms | UNIVERSITY OF ROCHESTER (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130096175-A1 | Compounds and Methods for Altering Lifespan of Eukaryotic Organisms | SOUTHERN RESEARCH INSTITUTE (US) | 2013-04-18 | — | — | US | disclosed |
| EP-2501229-A1 | COMPOUNDS AND METHODS FOR ALTERING LIFESPAN OF EUKARYOTIC ORGANISMS | University Of Rochester (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011062964-A1 | COMPOUNDS AND METHODS FOR ALTERING LIFESPAN OF EUKARYOTIC ORGANISMS | UNIVERSITY OF ROCHESTER (US) | 2011-05-26 | — | — | WO | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |