SCHEMBL1766148

SCHEMBL1766148

N[C@@H]1CCC[C@H]1OC(=O)NCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCHE P06276 19/20 0.59
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
CES2 O00748 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766150 1.00 BCHE (0.59) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL23300635 0.83 BCHE (0.59) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL27721872 0.82 BCHE (0.61) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL27742584 0.81 F2 (0.63) BCHEUSP2ALDH1A1HPGD
SCHEMBL28896375 0.78 F2 (0.51) BCHEUSP2ALDH1A1HPGD
SCHEMBL1024756 0.78 BCHE (0.53) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL27652150 0.78 HDAC3 (0.60) BCHEUSP2ALDH1A1HPGD
SCHEMBL17346771 0.77 HPGD (0.59) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL2575072 0.77 BCHE (0.55) BCHEUSP2ALDH1A1HPGDCES2
SCHEMBL27810920 0.77 BCHE (0.61) BCHEUSP2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319825-A1 ENZYMATIC SYNTHESIS OF ENANTIOMERICALLY ENRICHED DERIVATIVES OF CIS- AND TRANS-CYCLOPENTANE-1,2-DIAMINES EntreChem, S.L. (ES) 2011-05-11 EP disclosed