Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711033 | 0.86 | HRH3 (0.71) | SPHK1HRH3L3MBTL1ACHECA12 | |
| SCHEMBL17660231 | 0.84 | SPHK1 (0.58) | SPHK1HRH3L3MBTL1ACHESPHK2 | |
| SCHEMBL13489995 | 0.82 | SPHK1 (0.50) | SPHK1HRH3ACHECCR3SIGMAR1 | |
| SCHEMBL15922472 | 0.82 | SPHK1 (0.68) | SPHK1HRH3ACHELTA4HKCNH2 | |
| SCHEMBL13006766 | 0.82 | HRH3 (0.65) | HRH3L3MBTL1LTA4HHRH1SIGMAR1 | |
| SCHEMBL5943690 | 0.81 | SPHK1 (0.55) | SPHK1SPHK2LMNAHTR2AHTR2C | |
| SCHEMBL15242106 | 0.80 | HRH3 (0.65) | HRH3L3MBTL1LTA4HHRH1SIGMAR1 | |
| SCHEMBL14100275 | 0.80 | SPHK1 (0.65) | SPHK1HRH3ACHELTA4HKCNH2 | |
| SCHEMBL14100186 | 0.80 | SPHK1 (0.53) | SPHK1HRH3L3MBTL1ACHESPHK2 | |
| SCHEMBL1457116 | 0.79 | HTR2A (0.64) | SPHK1HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160096832-A1 | KINASE INHIBITORS | ALLERGAN, INC. | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096832-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | SPHK1 808/4885HRH3 3666/4885L3MBTL1 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.