SCHEMBL1766587

SCHEMBL1766587

O=C(Nc1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F)c1ccc(F)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
RXFP1 Q9HBX9 9/20 0.43
HTR1F P30939 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
NTRK1 P04629 1/20 0.39
KDM4E B2RXH2 1/20 0.39
KCNK3 O14649 1/20 0.39
KCNK9 Q9NPC2 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
NR1H4 Q96RI1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766565 0.95 CA12 (0.41) CA12CA9RXFP1HTR1FMEN1
SCHEMBL1766325 0.93 RXFP1 (0.48) CA12CA9RXFP1KCNK3KCNK9
SCHEMBL1766801 0.93 MEN1 (0.46) CA12CA9RXFP1HTR1FMEN1
SCHEMBL1766599 0.91 KCNJ11 (0.42) RXFP1KMT2ACYP1A2TSHRKDM4E
SCHEMBL20846832 0.90 RXFP1 (0.39) RXFP1PPARGNR1H4
SCHEMBL22212786 0.90 KDM4E (0.47) CA12CA9RXFP1HTR1FMEN1
SCHEMBL20846796 0.90 RXFP1 (0.45) CA12CA9RXFP1HTR1FMEN1
SCHEMBL20839518 0.90 CA12 (0.39) CA12CA9RXFP1HTR1FMEN1
SCHEMBL1766763 0.90 RXFP1 (0.52) RXFP1PPARGPPARDPPARANR1H4
SCHEMBL29422290 0.89 RXFP1 (0.44) CA12CA9RXFP1HTR1FMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2529620-B1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES MITSUI CHEMICALS AGRO INC (JP) 2020-07-15 EP claimed
EP-3684181-B1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2025-10-22 EP disclosed
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-08-05 US disclosed
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-07-20 US disclosed
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-07-20 US disclosed
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS AGRO, INC. (JP) 2023-07-11 US disclosed
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS AGRO, INC. (JP) 2023-07-11 US disclosed
EP-3081552-B1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT MITSUI CHEMICALS AGRO INC (JP) 2021-03-03 EP disclosed
US-20200281914-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS AGRO, INC. (JP) 2020-09-10 US disclosed
US-20200281914-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS AGRO, INC. (JP) 2020-09-10 US disclosed
US-9237745-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative MITSUI CHEMICALS AGRO, INC. (JP) 2016-01-19 US disclosed
US-20130310459-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2013-11-21 US disclosed
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS ARGO, INC. (JP) 2013-09-05 US disclosed
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS ARGO, INC. (JP) 2013-09-05 US disclosed
EP-2529620-A1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES Mitsui Chemicals Agro, Inc. (JP) 2012-12-05 EP disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
WO-2011093415-A1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES 三井化学アグロ株式会社 (JP) 2011-08-04 WO disclosed
CN-102119143-A Amide derivative, pest control agent containing the same, and method of using the pest control agent MITSUI CHEMICALS AGRO INC 2011-07-06 CN disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT CA12 3321/4885CA9 3074/4885RXFP1 1867/4885
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MTX1, ENPP1, CAT CA12 3321/4885CA9 3074/4885RXFP1 1867/4885
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT CA12 3321/4885CA9 3074/4885RXFP1 1867/4885
US-20130310459-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-0, H1-4 CA12 2339/4885CA9 2804/4885RXFP1 2224/4885
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 CA12 2667/4885CA9 2585/4885RXFP1 2628/4885
US-20200281914-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MTX1, ENPP1, CAT CA12 3321/4885CA9 3074/4885RXFP1 1867/4885
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-0, H1-4 CA12 2339/4885CA9 2804/4885RXFP1 2224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.