Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17645783 | 0.79 | CCNT1 (0.41) | BTKCDK9CCNT1 | |
| SCHEMBL17660349 | 0.78 | BTK (0.44) | BTK | |
| SCHEMBL30950594 | 0.77 | BTK (0.43) | BTKENPP1 | |
| SCHEMBL17645984 | 0.77 | MAPK14 (0.42) | BTK | |
| SCHEMBL17646003 | 0.77 | MAPK14 (0.42) | BTK | |
| SCHEMBL17645796 | 0.77 | BTK (0.42) | BTK | |
| SCHEMBL17646036 | 0.76 | BTK (0.59) | BTK | |
| SCHEMBL17645701 | 0.76 | BTK (0.59) | BTK | |
| SCHEMBL30950575 | 0.76 | BTK (0.59) | BTK | |
| Hydrochloric Acid SCHEMBL30950588 | 0.76 | BTK (0.58) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016057500-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-14 | — | — | WO | disclosed |