Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17646035 | 1.00 | BTK (0.56) | BTKLCK | |
| SCHEMBL17645742 | 0.91 | BTK (0.57) | BTKLCK | |
| SCHEMBL17664630 | 0.89 | BTK (0.57) | BTKLCK | |
| SCHEMBL17645864 | 0.89 | BTK (0.56) | BTKLCK | |
| SCHEMBL17645738 | 0.86 | BTK (0.44) | BTKLCK | |
| SCHEMBL17646023 | 0.85 | BTK (0.47) | BTKLCK | |
| SCHEMBL17646059 | 0.83 | BTK (0.68) | BTKLCK | |
| SCHEMBL17646018 | 0.83 | BTK (0.59) | BTKLCK | |
| SCHEMBL17645677 | 0.83 | BTK (0.63) | BTKLCK | |
| SCHEMBL17645787 | 0.83 | BTK (0.58) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016057500-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-14 | — | — | WO | disclosed |