SCHEMBL17674145

SCHEMBL17674145

CC=C(C(=O)OCC)[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 7/20 0.46
LMNA P02545 3/20 0.46
HPGD P15428 1/20 0.46
GLO1 Q04760 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPT P10636 1/20 0.36
CYP2D6 P10635 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FAAH O00519 2/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 3/20 0.36
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALOX15 P16050 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17674143 1.00 CYP1A2 (0.54) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL14706091 1.00 CYP1A2 (0.54) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL23941092 0.84 CYP1A2 (0.51) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL10717796 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL6835113 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL1294624 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL6835112 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL1294629 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL1294626 0.82 CYP1A2 (0.50) CYP1A2CYP2C19ALDH1A1LMNAHPGD
SCHEMBL165898 0.81 CYP1A2 (0.49) CYP1A2CYP2C19ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed