Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.79 |
| ▸ | EGFR | P00533 | 13/20 | 0.79 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | TEC | P42680 | 1/20 | 0.60 |
| ▸ | TXK | P42681 | 1/20 | 0.60 |
| ▸ | BLK | P51451 | 1/20 | 0.60 |
| ▸ | BMX | P51813 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675364 | 0.88 | BTK (1.00) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675197 | 0.86 | EGFR (0.82) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675434 | 0.82 | EGFR (1.00) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17683773 | 0.81 | EGFR (0.80) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675237 | 0.80 | EGFR (0.80) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675574 | 0.78 | EGFR (0.81) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675591 | 0.77 | EGFR (0.79) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675479 | 0.77 | EGFR (0.79) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675514 | 0.76 | BTK (0.78) | BTKEGFRERBB2TECTXK | |
| SCHEMBL17675227 | 0.76 | EGFR (0.75) | BTKEGFRERBB2TECTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | claimed |