Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.63 |
| ▸ | EGFR | P00533 | 11/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TEC | P42680 | 2/20 | 0.52 |
| ▸ | TXK | P42681 | 2/20 | 0.52 |
| ▸ | BLK | P51451 | 2/20 | 0.52 |
| ▸ | BMX | P51813 | 2/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675203 | 0.88 | BTK (0.73) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675320 | 0.86 | BTK (0.61) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675235 | 0.86 | BTK (0.73) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675541 | 0.85 | BTK (0.65) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675365 | 0.85 | BTK (0.59) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675303 | 0.82 | BTK (0.70) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675502 | 0.81 | BTK (0.67) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17683769 | 0.80 | BTK (0.70) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675263 | 0.80 | BTK (0.66) | BTKEGFRCYP3A4KDRTEC | |
| SCHEMBL17675221 | 0.79 | BTK (0.77) | BTKEGFRKDRTECTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | disclosed |