Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2G | O75747 | 5/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 15/20 | 0.66 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323362 | 1.00 | PIK3C2G (0.69) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851606 | 0.94 | PIK3C2G (0.69) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL17675702 | 0.91 | PI4KB (0.59) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL17675704 | 0.91 | PIK3C2G (0.70) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851576 | 0.89 | PIK3C2G (0.75) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851742 | 0.88 | PIK3C2G (0.74) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851725 | 0.88 | PIK3C2G (0.74) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851853 | 0.87 | PIK3C2G (0.71) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851649 | 0.86 | PIK3C2G (0.73) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB | |
| SCHEMBL16490471 | 0.85 | PI4KB (0.59) | PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-01-20 | — | — | US | disclosed |
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-17 | — | — | US | disclosed |
| WO-2020146657-A1 | PI4-KINASE INHIBITORS WITH ANTI-CANCER ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
| US-10428060-B2 | PI-kinase inhibitors with anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-10-01 | — | — | US | disclosed |
| US-10428060-B2 | PI-kinase inhibitors with anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180170924-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2018-06-21 | — | — | US | disclosed |
| US-20180170924-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2018-06-21 | — | — | US | disclosed |
| US-9926309-B2 | Pi-kinase inhibitors with anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926309-B2 | Pi-kinase inhibitors with anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-27 | — | — | US | disclosed |
| WO-2017147526-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20160194314-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-07 | — | — | US | disclosed |
| US-20160194314-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-07 | — | — | US | disclosed |
| US-9309236-B2 | PI-kinase inhibitors with broad spectrum anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | PIP4K2A, PIP5K1A, PIP4K2C | PIK3C2G 100/4885PIK3CD 20/4885PIK3CG 21/4885 |
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | PIK3C2G 98/4885PIK3CD 23/4885PIK3CG 25/4885 |
| US-20180170924-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | PIP4K2A, PIP5K1A, PIP4K2C | PIK3C2G 100/4885PIK3CD 20/4885PIK3CG 21/4885 |
| US-20160194314-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | PIP4K2A, PIP5K1A, PIP4K2C | PIK3C2G 100/4885PIK3CD 20/4885PIK3CG 21/4885 |
| US-10428060-B2 | PI-kinase inhibitors with anti-infective activity | PIP4K2A, PIP5K1A, PIP4K2C | PIK3C2G 100/4885PIK3CD 20/4885PIK3CG 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.