Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MST1R | Q04912 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326483 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL10327021 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL11445118 | 0.80 | CREBBP (0.58) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL30418670 | 0.80 | CREBBP (0.58) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL13802296 | 0.77 | PBRM1 (0.43) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL13802369 | 0.77 | PBRM1 (0.43) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL30634575 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL24852681 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL5579750 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL24852596 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |