Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRAT | O95237 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Neamine SCHEMBL2736468 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL29587258 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL12591591 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL14445338 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL12961240 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL219578 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL11590075 | 1.00 | LRAT (1.00) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL6446250 | 0.99 | LRAT (0.97) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL3669932 | 0.99 | LRAT (0.97) | LRATLMNAKDM4EALOX15MEN1 | |
| Neamine SCHEMBL1762107 | 0.99 | LRAT (0.97) | LRATLMNAKDM4EALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673281-B1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | disclosed |