Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016246 | 1.00 | GABRR1 (0.39) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL15641135 | 0.87 | GABRR1 (0.33) | GABRR1LMNACYP1A2TSHRKDM4E | |
| SCHEMBL2520512 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12238423 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12239045 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12238424 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12238422 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12239043 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL12239044 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL1897862 | 0.85 | GABRR1 (0.35) | GABRR1LMNACYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673281-B1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | disclosed |