Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987666 | 0.76 | ADORA2A (0.60) | ADORA2AADORA2B | |
| SCHEMBL27272822 | 0.76 | ADORA2A (0.60) | ADORA2AADORA2B | |
| SCHEMBL30645727 | 0.75 | PDGFRA (0.40) | ADORA2AADORA2B | |
| SCHEMBL20520407 | 0.75 | PDGFRA (0.40) | ADORA2AADORA2B | |
| SCHEMBL24752903 | 0.74 | SCN9A (0.40) | ADORA2AADORA2B | |
| SCHEMBL17673664 | 0.74 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL30958149 | 0.74 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL17673835 | 0.74 | LSS (0.34) | ADORA2AADORA2B | |
| SCHEMBL17678217 | 0.72 | ADORA2A (0.32) | ADORA2AADORA2B | |
| SCHEMBL26741169 | 0.70 | ADORA2A (0.35) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016057834-A9 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-04-13 | — | — | WO | disclosed |
| WO-2016057834-A1 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. (US) | 2016-04-14 | — | — | WO | disclosed |