Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.90 |
| ▸ | RAF1 | P04049 | 9/20 | 0.90 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.90 |
| ▸ | JAK2 | O60674 | 1/20 | 0.90 |
| ▸ | ABL1 | P00519 | 1/20 | 0.90 |
| ▸ | EGFR | P00533 | 1/20 | 0.90 |
| ▸ | LCK | P06239 | 1/20 | 0.90 |
| ▸ | CSF1R | P07333 | 1/20 | 0.90 |
| ▸ | LYN | P07948 | 1/20 | 0.90 |
| ▸ | RET | P07949 | 1/20 | 0.90 |
| ▸ | MET | P08581 | 1/20 | 0.90 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.90 |
| ▸ | KIT | P10721 | 1/20 | 0.90 |
| ▸ | BCR | P11274 | 1/20 | 0.90 |
| ▸ | FER | P16591 | 1/20 | 0.90 |
| ▸ | FLT1 | P17948 | 1/20 | 0.90 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.90 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.90 |
| ▸ | KDR | P35968 | 1/20 | 0.90 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cep-32496 SCHEMBL29697285 | 0.94 | BRAF (1.00) | BRAFRAF1RIPK2JAK2ABL1 | |
| Cep-32496 SCHEMBL29351427 | 0.94 | BRAF (1.00) | BRAFRAF1RIPK2JAK2ABL1 | |
| Cep-32496 SCHEMBL1015932 | 0.94 | BRAF (1.00) | BRAFRAF1RIPK2JAK2ABL1 | |
| Cep-32496 SCHEMBL29726019 | 0.94 | BRAF (0.98) | BRAFRAF1RIPK2JAK2ABL1 | |
| Cep-32496 SCHEMBL18155156 | 0.94 | BRAF (0.98) | BRAFRAF1RIPK2JAK2ABL1 | |
| SCHEMBL1011900 | 0.92 | BRAF (0.90) | BRAFRAF1RIPK2JAK2ABL1 | |
| SCHEMBL16156073 | 0.91 | BRAF (0.93) | BRAFRAF1RIPK2JAK2ABL1 | |
| SCHEMBL1013252 | 0.91 | BRAF (0.90) | BRAFRAF1RIPK2JAK2ABL1 | |
| SCHEMBL17053430 | 0.91 | BRAF (0.92) | BRAFRAF1RIPK2JAK2ABL1 | |
| SCHEMBL1011649 | 0.90 | BRAF (0.91) | BRAFRAF1RIPK2JAK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160101106-A1 | METHODS FOR TREATING HCV INFECTION | INHIBIKASE THERAPEUTICS, INC. (US) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101106-A1 | METHODS FOR TREATING HCV INFECTION | HAVCR2, RAF1, BRAF | BRAF 3/4885RAF1 2/4885RIPK2 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.