SCHEMBL17680667

SCHEMBL17680667

Bc1cccc2c1O[C@H](C)CC(=O)N2

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 20/20 0.71
BRD4 O60885 16/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17680581 0.83 CREBBP (1.00) CREBBPBRD4
SCHEMBL17673154 0.82 CREBBP (0.71) CREBBPBRD4
SCHEMBL19518217 0.82 CREBBP (0.71) CREBBPBRD4
SCHEMBL17673195 0.78 CREBBP (0.72) CREBBPBRD4
SCHEMBL17680223 0.78 CREBBP (1.00) CREBBPBRD4
SCHEMBL19531721 0.77 CREBBP (0.77) CREBBPBRD4
SCHEMBL10068846 0.76 PARP1 (0.56) CREBBPBRD4
SCHEMBL19538387 0.75 CREBBP (0.73) CREBBPBRD4
SCHEMBL17680578 0.75 CREBBP (1.00) CREBBPBRD4
SCHEMBL17673219 0.75 CREBBP (0.67) CREBBPBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016055028-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2016-04-14 WO disclosed