Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369193 | 0.80 | CREBBP (0.44) | CREBBPBRD4 | |
| SCHEMBL17680951 | 0.80 | CREBBP (0.43) | CREBBPBRD4 | |
| SCHEMBL17680748 | 0.78 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL22368856 | 0.77 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL17680876 | 0.74 | CREBBP (0.61) | CREBBPBRD4 | |
| SCHEMBL22368933 | 0.74 | CREBBP (0.65) | CREBBPBRD4 | |
| SCHEMBL22368835 | 0.74 | CREBBP (0.67) | CREBBPBRD4 | |
| SCHEMBL22368849 | 0.73 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL22928146 | 0.73 | CREBBP (0.39) | CREBBPBRD4 | |
| SCHEMBL22369217 | 0.72 | CREBBP (0.64) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |