Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959766 | 0.88 | BCL2 (0.80) | BCL2 | |
| SCHEMBL1541118 | 0.87 | BCL2 (0.72) | BCL2 | |
| SCHEMBL1957634 | 0.84 | BCL2 (0.81) | BCL2 | |
| SCHEMBL1541585 | 0.84 | BCL2 (0.72) | BCL2 | |
| SCHEMBL2830924 | 0.84 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1957020 | 0.84 | BCL2 (0.80) | BCL2 | |
| SCHEMBL1955720 | 0.84 | BCL2 (0.84) | BCL2 | |
| SCHEMBL1540777 | 0.83 | BCL2 (0.68) | BCL2 | |
| SCHEMBL1955098 | 0.82 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1955324 | 0.82 | BCL2 (0.88) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315488-B2 | Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE INC. (US) | 2016-04-19 | — | — | US | disclosed |