SCHEMBL17682360

SCHEMBL17682360

NC(=O)[C@@H](N)CCCCNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.63
▸ NOD1 Q9Y239 5/20 0.48
▸ CCKAR P32238 5/20 0.44
▸ CCKBR P32239 5/20 0.44
▸ FOLH1 Q04609 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21099666 0.99 GLP1R (0.65) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL20653031 0.98 GLP1R (0.66) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL19034982 0.94 GLP1R (0.65) GLP1RNOD1FOLH1
SCHEMBL19034800 0.94 GLP1R (0.65) GLP1RNOD1FOLH1
SCHEMBL21099901 0.93 GLP1R (0.62) GLP1RNOD1CCKARCCKBR
SCHEMBL19034932 0.93 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL19034971 0.93 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24249859 0.92 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL19034796 0.92 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL21110472 0.92 GLP1R (0.68) GLP1RNOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016055610-A1 STABLE GLP-1 BASED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS NOVO NORDISK A/S (DK) 2016-04-14 — — WO disclosed
US-20160102129-A1 Stable GLP-1 Based GLP-1/Glucagon Receptor Co-Agonists NOVO NORDISK A/S (DK) 2016-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160102129-A1 Stable GLP-1 Based GLP-1/Glucagon Receptor Co-Agonists GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 423/4885CCKAR 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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