Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768406 | 0.80 | TOP1 (0.41) | ALDH1A1KDM4EMAPTCYP3A4TDP1 | |
| SCHEMBL1840267 | 0.79 | CYP3A4 (0.41) | SCN9AL3MBTL1ALDH1A1TRPA1HSD11B1 | |
| SCHEMBL1768448 | 0.78 | CYP3A4 (0.48) | KDM4ECYP3A4TDP1 | |
| SCHEMBL4006970 | 0.74 | TOP1 (0.42) | ALDH1A1KDM4EMAPTCYP3A4TDP1 | |
| SCHEMBL21041133 | 0.74 | FFAR4 (0.41) | FFAR4 | |
| SCHEMBL1768566 | 0.74 | CYP3A4 (0.39) | CYP3A4TDP1 | |
| SCHEMBL5195630 | 0.73 | APP (0.44) | ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL1768199 | 0.72 | TDP1 (0.41) | ALDH1A1KDM4ECYP3A4TDP1 | |
| SCHEMBL1838651 | 0.70 | GAA (0.37) | SCN9AL3MBTL1ALDH1A1TRPA1KDM4E | |
| SCHEMBL1768305 | 0.70 | MYC (0.41) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |