Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333875 | 0.87 | TDP1 (0.50) | TDP1CYP3A4CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL29635182 | 0.83 | TDP1 (0.50) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL4004840 | 0.83 | TDP1 (0.50) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL28765143 | 0.83 | CYP3A4 (0.55) | TDP1CYP3A4DRD1ESR1ESR2 | |
| SCHEMBL7799500 | 0.81 | TDP1 (0.48) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL32685426 | 0.81 | TDP1 (0.48) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL28152682 | 0.80 | TDP1 (0.42) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL19664922 | 0.80 | TDP1 (0.42) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| Bromide SCHEMBL6675138 | 0.79 | TDP1 (0.46) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 | |
| SCHEMBL28427105 | 0.79 | TDP1 (0.46) | TDP1CYP3A4CYP2A6DRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112642489-B | Homogeneous bimetallic complex catalyst, preparation method thereof and application thereof in preparation of aldehyde from alcohol | 山东新和成药业有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-107175134-B | It is a kind of to be used to prepare 3-aminophenylacetylene or the composition of its salt and application thereof | 成都西岭源药业有限公司 | 2018-03-23 | — | — | CN | claimed |
| EP-1341798-A1 | CHIRAL DIPHOSPHINES AND THEIR METAL COMPLEXES | PPG-Sipsy (FR) | 2003-09-10 | — | — | EP | claimed |
| WO-2002040492-A1 | CHIRAL DIPHOSPHINES AND THEIR METAL COMPLEXES | PPG-SIPSY (FR) | 2002-05-23 | — | — | WO | claimed |
| US-11739103-B2 | Processes for preparing a pan-JAK inhibitor and related intermediate compounds | Theravance Biopharma R&D LP, LLC (US) | 2023-08-29 | — | — | US | disclosed |
| CN-114085200-B | Method for preparing 2, 5-furandicarboxylic acid by using 2-furancarboxylic acid as raw material through one-pot method | 华东师范大学 | 2023-03-14 | — | — | CN | disclosed |
| US-20220112219-A1 | PROCESSES FOR PREPARING A PAN-JAK INHIBITOR AND RELATED INTERMEDIATE COMPOUNDS | THERAVANCE BIOPHARMA R&D IP, LLC | 2022-04-14 | — | — | US | disclosed |
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114031494-A | Method for preparing carboxylic acid by catalyzing reaction of unsaturated hydrocarbon and formic acid by using catalyst containing noble metal compound | 华东师范大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-110105308-A | Preparation method of vortioxetine | 山东京卫制药有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-110105309-A | A kind of preparation method lying prostrate sulphur Xi Ting | 山东京卫制药有限公司 | 2019-08-09 | — | — | CN | disclosed |
| WO-2013035650-A1 | METHOD FOR PRODUCING ALPHA - HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-14 | — | — | WO | disclosed |
| EP-2379575-A1 | HYDROPHOSPHORYLATION OF PHOSPHONOUS ACID DERIVATIVES FOR FLAME RETARDANTS | Clariant International Ltd. (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2011061439-A1 | CATALYTIC PHOSPHINATION METHOD | UNIVERSITE DE STRASBOURG (FR) | 2011-05-26 | — | — | WO | disclosed |
| WO-2010069421-A1 | HYDROPHOSPHORYLATION OF PHOSPHONOUS ACID DERIVATIVES FOR FLAME RETARDANTS | CLARIANT INTERNATIONAL LTD (CH) | 2010-06-24 | — | — | WO | disclosed |
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2004084834-A2 | CHIRAL POROUS METAL PHOSPHONATES FOR HETEROGENEOUS ASYMMETRIC CATALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-10-07 | — | — | WO | disclosed |
| EP-0975574-A1 | PROCESS TO PREPARE A PENTENOIC ACID DERIVATIVE | DSM N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998038151-A1 | PROCESS TO PREPARE A PENTENOIC ACID DERIVATIVE | DSM N.V. (NL) | 1998-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112219-A1 | PROCESSES FOR PREPARING A PAN-JAK INHIBITOR AND RELATED INTERMEDIATE COMPOUNDS | JAK1, JAK3, JAK2 | TDP1 2495/4885CYP3A4 825/4885CYP2A6 2400/4885 |
| US-11739103-B2 | Processes for preparing a pan-JAK inhibitor and related intermediate compounds | JAK1, JAK3, JAK2 | TDP1 2495/4885CYP3A4 825/4885CYP2A6 2400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.