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Sugi Predict / Compounds / Marbofloxacin

Marbofloxacin

Marbofloxacin

SCHEMBL1768472

CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2OCN4C)CC1.O=CO

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.93
▸ ALDH1A1 P00352 6/20 0.62
▸ HPGD P15428 4/20 0.62
▸ HSD17B10 Q99714 3/20 0.62
▸ ALB P02768 1/20 0.62
▸ HRH3 Q9Y5N1 1/20 0.62
▸ TUBB4A P04350 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ TUBB P07437 1/20 0.61
▸ TUBA3C P0DPH7 1/20 0.61
▸ TUBA1B P68363 1/20 0.61
▸ TUBA4A P68366 1/20 0.61
▸ TUBB4B P68371 1/20 0.61
▸ TUBB3 Q13509 1/20 0.61
▸ TUBB2A Q13885 1/20 0.61
▸ TUBB8 Q3ZCM7 1/20 0.61
▸ TUBA3E Q6PEY2 1/20 0.61
▸ TUBA1A Q71U36 1/20 0.61
▸ SLC47A1 Q96FL8 1/20 0.61
▸ TUBA1C Q9BQE3 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Marbofloxacin SCHEMBL29355042 0.96 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10ALB
Marbofloxacin SCHEMBL134860 0.96 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10ALB
Marbofloxacin SCHEMBL10563057 0.95 KDM4E (0.98) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL12637996 0.93 KDM4E (0.94) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL16518628 0.88 KDM4E (0.85) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL9533526 0.88 KDM4E (0.84) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL12665530 0.88 KDM4E (0.84) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL9533821 0.87 KDM4E (0.83) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL12638277 0.87 KDM4E (0.82) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL10561493 0.87 KDM4E (0.82) KDM4EALDH1A1HPGDHSD17B10ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249749-B Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2024-03-22 — — CN claimed
CN-114249749-A Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2022-03-29 — — CN claimed
CN-114249749-B Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2024-03-22 — — CN disclosed
CN-114249749-B Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2024-03-22 — — CN disclosed
CN-114249749-B Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2024-03-22 — — CN disclosed
CN-114249749-A Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2022-03-29 — — CN disclosed
CN-114249749-A Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2022-03-29 — — CN disclosed
CN-114249749-A Conversion method of marbofloxacin formate 天象生物药业邢台有限责任公司 2022-03-29 — — CN disclosed
EP-2501680-B1 A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) 2016-02-10 — — EP disclosed
CN-102712598-A A process for a preparation of marbofloxacin and intermediate thereof KRKA TOVARNA ZDRAVIL D D NOVO MESTO 2012-10-03 — — CN disclosed
EP-2501680-A1 A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO et al (SI) 2012-09-26 — — EP disclosed
EP-2332916-A2 A process for a preparation of marbofloxacin and intermediate thereof Krka Tovarna Zdravil, D.D., Novo Mesto (SI) 2011-06-15 — — EP disclosed
WO-2011061292-A1 A PROCESS FOR A PREPARATION OF MARBOFLOXACIN AND INTERMEDIATE THEREOF KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) 2011-05-26 — — WO disclosed