Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.77 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.77 |
| ▸ | HCK | P08631 | 8/20 | 0.72 |
| ▸ | SRC | P12931 | 7/20 | 0.72 |
| ▸ | GSK3A | P49840 | 4/20 | 0.72 |
| ▸ | SYK | P43405 | 4/20 | 0.72 |
| ▸ | GSK3B | P49841 | 1/20 | 0.72 |
| ▸ | BRAF | P15056 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685247 | 0.94 | MAPK14 (0.79) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL17685289 | 0.94 | MAPK14 (0.78) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL17685100 | 0.93 | MAPK14 (0.76) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL12540424 | 0.90 | MAPK14 (0.79) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL17965530 | 0.89 | MAPK14 (0.78) | MAPK14MAPK12HCKSRC | |
| SCHEMBL13504135 | 0.88 | MAPK14 (0.77) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL17685081 | 0.88 | MAPK14 (0.71) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL2516503 | 0.88 | MAPK14 (0.84) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL2529985 | 0.87 | MAPK14 (0.74) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL2568987 | 0.87 | MAPK14 (1.00) | MAPK14MAPK12HCKSRCGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370429-B1 | P38 MAP KINASE INHIBITORS | RESPIVERT LTD (GB) | 2016-04-20 | — | — | EP | claimed |