⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715867 | 0.96 | GSK3B (1.00) | — | |
| SCHEMBL33524954 | 0.96 | — | — | |
| SCHEMBL10990 | 0.96 | — | — | |
| SCHEMBL7021498 | 0.96 | — | — | |
| SCHEMBL693917 | 0.96 | GSK3B (1.00) | — | |
| Charcoal, Activated SCHEMBL8357494 | 0.92 | — | — | |
| SCHEMBL8835188 | 0.92 | — | — | |
| SCHEMBL9862604 | 0.92 | GSK3A (0.92) | — | |
| Charcoal, Activated SCHEMBL4128314 | 0.92 | GSK3A (0.92) | — | |
| SCHEMBL4657701 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496270-B1 | ZIRCONIUM-RADIOLABELED, CYSTEINE ENGINEERED ANTIBODY CONJUGATES | HOFFMANN LA ROCHE (CH) | 2018-01-31 | — | — | EP | disclosed |
| CN-102596260-B | Radiolabeled, the cysteine engineered antibody conjugates of zirconium | 弗·哈夫曼-拉罗切有限公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2496270-A1 | ZIRCONIUM-RADIOLABELED, CYSTEINE ENGINEERED ANTIBODY CONJUGATES | F. Hoffmann-La Roche AG (CH) | 2012-09-12 | — | — | EP | disclosed |
| CN-102596260-A | Zirconium-radiolabeled, cysteine engineered antibody conjugates | HOFFMANN LA ROCHE | 2012-07-18 | — | — | CN | disclosed |
| WO-2011056983-A1 | ZIRCONIUM-RADIOLABELED, CYSTEINE ENGINEERED ANTIBODY CONJUGATES | GENENTECH, INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20100111856-A1 | ZIRCONIUM-RADIOLABELED, CYSTEINE ENGINEERED ANTIBODY CONJUGATES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-06 | — | — | US | disclosed |