Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 16/20 | 0.47 |
| ▸ | CCNH | P51946 | 13/20 | 0.47 |
| ▸ | CDK9 | P50750 | 12/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.47 |
| ▸ | CCNK | O75909 | 9/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 9/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CDK13 | Q14004 | 7/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.37 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654932 | 0.92 | CDK7 (0.48) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL16655068 | 0.87 | CDK7 (0.53) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL16655066 | 0.87 | CDK7 (0.53) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL18074072 | 0.86 | CDK7 (0.49) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL21397489 | 0.86 | CDK7 (0.49) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL21397206 | 0.86 | CDK7 (0.49) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL16665647 | 0.86 | CDK7 (0.49) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL17688419 | 0.84 | CDK7 (0.42) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL16655064 | 0.84 | CCNK (0.52) | CDK7CCNHCDK9CCNT1CCNK | |
| SCHEMBL17688399 | 0.84 | CDK7 (0.43) | CDK7CCNHCDK9CCNT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016058544-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2016-04-21 | — | — | WO | disclosed |