Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | CYCS | P99999 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689321 | 1.00 | ABCG2 (0.46) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL12392100 | 0.99 | ABCG2 (0.45) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL12450828 | 0.99 | ABCG2 (0.45) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL17688986 | 0.97 | ABCG2 (0.48) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL12392075 | 0.97 | ABCG2 (0.48) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL12451490 | 0.97 | ABCG2 (0.48) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL24689530 | 0.96 | ABCG2 (0.43) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL17688989 | 0.95 | ABCG2 (0.50) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL24689574 | 0.95 | ABCG2 (0.50) | ABCG2TOP1CYCSSMN1; SMN2MAPT | |
| SCHEMBL12451489 | 0.94 | ABCG2 (0.52) | ABCG2TOP1CYCSSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315510-B2 | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2016-04-19 | — | — | US | disclosed |