Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878224 | 0.82 | CYP3A4 (0.47) | CYP3A4TRPA1GABRA1GABRB2 | |
| SCHEMBL75112 | 0.79 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1ALDH1A1 | |
| SCHEMBL10624633 | 0.79 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL6544263 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL58726 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL29648814 | 0.79 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1ALDH1A1 | |
| SCHEMBL31318368 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL5576974 | 0.78 | CYP3A4 (0.45) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL11761677 | 0.77 | CYP3A4 (0.38) | CYP3A4TSHR | |
| SCHEMBL11871641 | 0.77 | CYP3A4 (0.54) | CYP3A4TRPA1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107473198-B | A method of manufacturing carbonyl fluoride using to trichloromethyl phenylisocyanate | 淄博飞源化工有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-107473198-A | It is a kind of to utilize the method that carbonyl fluoride is manufactured to trichloromethyl phenylisocyanate | 淄博飞源化工有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-101016255-A | Preparation method of trichloromethylbenzeneisocyanate | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-08-15 | — | — | CN | claimed |
| EP-0152310-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ANILINES | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | claimed |
| EP-0129214-B1 | METHOD FOR THE PREPARATION OF BENZENAMINES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-10-29 | — | — | EP | claimed |
| EP-0129214-A1 | Method for the preparation of benzenamines | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-12-27 | — | — | EP | claimed |
| US-4466927-A | FROM N-(TRIFLUOROMETHYL)ANTHRANILOYL FLUORIDE WITH HYDROGEN FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-21 | — | — | US | claimed |
| CN-118894794-A | Method for preparing dichloro methyl phenyl isocyanate by continuous flow photocatalysis | 乐平市赛复乐医药化工有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-110668955-A | Synthesis method of o-amino benzotrifluoride | 江苏丰华化学工业有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-107473198-B | A method of manufacturing carbonyl fluoride using to trichloromethyl phenylisocyanate | 淄博飞源化工有限公司 | 2018-07-13 | — | — | CN | disclosed |
| CN-107473198-B | A method of manufacturing carbonyl fluoride using to trichloromethyl phenylisocyanate | 淄博飞源化工有限公司 | 2018-07-13 | — | — | CN | disclosed |
| CN-107473198-B | A method of manufacturing carbonyl fluoride using to trichloromethyl phenylisocyanate | 淄博飞源化工有限公司 | 2018-07-13 | — | — | CN | disclosed |
| CN-108191673-A | The method of the Synthesis liquid processing of right/o-trifluoromethyl aniline | 江苏优普生物化学科技股份有限公司 | 2018-06-22 | — | — | CN | disclosed |
| US-4748277-A | FLUORINATION AND HYDROLYSIS OF TRIHALOMETHYLPHENYL ISOCYANATE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-05-31 | — | — | US | disclosed |
| EP-0152310-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ANILINES | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | disclosed |
| EP-0129214-B1 | METHOD FOR THE PREPARATION OF BENZENAMINES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0152310-A1 | Process for the preparation of trifluoromethyl anilines | RHONE-POULENC CHIMIE (FR) | 1985-08-21 | — | — | EP | disclosed |
| EP-0129214-A1 | Method for the preparation of benzenamines | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4481370-A | REACTING HYDROGEN FLUORIDE WITH A PHENYL CARBAMIC FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4466927-A | FROM N-(TRIFLUOROMETHYL)ANTHRANILOYL FLUORIDE WITH HYDROGEN FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |