SCHEMBL17692159

SCHEMBL17692159

c1ccc2c(c1)-c1cccc3c(-c4cc(-c5ccc6ccc7cccnc7c6n5)c5cnccc5c4)ccc-2c13

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 3/20 0.43
CYP11B1 P15538 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
TSHR P16473 2/20 0.35
HIF1A Q16665 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 4/20 0.35
HTT P42858 3/20 0.35
POLB P06746 2/20 0.35
RAD52 P43351 1/20 0.35
CYP11B2 P19099 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MAPT P10636 3/20 0.34
CCR1 P32246 2/20 0.34
CCR5 P51681 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17692022 0.84 CYP11B1 (0.43) TNFCYP11B1L3MBTL1TSHRHIF1A
SCHEMBL17691876 0.82 CYP11B1 (0.43) TNFCYP11B1L3MBTL1TSHRHIF1A
SCHEMBL17491082 0.82 CCR1 (0.41) CYP11B1L3MBTL1TSHRHIF1AALDH1A1
SCHEMBL17229059 0.81 CYP11B1 (0.42) TNFCYP11B1L3MBTL1TSHRHIF1A
SCHEMBL17692080 0.81 CYP11B1 (0.45) TNFCYP11B1L3MBTL1TSHRHIF1A
SCHEMBL18904472 0.81 TSHR (0.48) L3MBTL1TSHRHIF1AALDH1A1HPGD
SCHEMBL17491093 0.80 CCR1 (0.47) L3MBTL1TSHRHIF1AALDH1A1HPGD
SCHEMBL23016293 0.80 TNF (0.44) TNFCYP11B1L3MBTL1ALDH1A1HPGD
SCHEMBL17899288 0.79 BRD4 (0.43) L3MBTL1TSHRHIF1AALDH1A1HPGD
SCHEMBL17692141 0.79 TNF (0.61) TNFCYP11B1L3MBTL1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed