⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17693387 | 1.00 | — | — | |
| SCHEMBL1106761 | 0.79 | — | — | |
| SCHEMBL9887868 | 0.76 | — | — | |
| SCHEMBL5414735 | 0.75 | — | — | |
| SCHEMBL11640523 | 0.74 | — | — | |
| Water SCHEMBL10632239 | 0.73 | — | — | |
| SCHEMBL13672921 | 0.72 | — | — | |
| SCHEMBL12943945 | 0.72 | — | — | |
| SCHEMBL16716219 | 0.72 | — | — | |
| SCHEMBL15609483 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617261-B2 | Substituted pyridinone compounds as MEK inhibitors | CMG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-20160108041-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS MEK INHIBITORS | CMG PHARMACEUTICAL CO., LTD. (KR) | 2016-04-21 | — | — | US | disclosed |