Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694793 | 0.87 | AR (0.45) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL12515796 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL17694826 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL17694760 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL17694797 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL14707389 | 0.81 | AR (0.48) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL17694758 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL14694892 | 0.80 | AR (0.67) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14695608 | 0.80 | AR (0.67) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14694893 | 0.80 | AR (0.67) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016058080-A1 | FLUORO-CHLORO BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2016-04-21 | — | — | WO | disclosed |