Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561877 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL16561886 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL17683644 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL17020327 | 1.00 | CYP2D6 (0.49) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL16361986 | 0.94 | CYP2D6 (0.45) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL16361966 | 0.94 | CYP2D6 (0.45) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL17853203 | 0.90 | CYP2D6 (0.48) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL16361965 | 0.90 | CYP2D6 (0.48) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL17695747 | 0.90 | CYP2D6 (0.48) | CYP2D6THRBHSD17B10PRKD3PRKCG | |
| SCHEMBL16361988 | 0.90 | CYP2D6 (0.48) | CYP2D6THRBHSD17B10PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | NATIONAL SCIENCE FOUNDATION | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | C1S, PYM1, DEGS1 | CYP2D6 276/4885THRB 3830/4885HSD17B10 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.