Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GCLC | P48506 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 2/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769614 | 1.00 | PMP22 (0.43) | PMP22NOS2NOS3NOS1BHMT | |
| SCHEMBL1769546 | 0.85 | PMP22 (0.37) | PMP22NOS2NOS3NOS1BHMT | |
| SCHEMBL1769545 | 0.85 | PMP22 (0.37) | PMP22NOS2NOS3NOS1BHMT | |
| SCHEMBL1768836 | 0.83 | GSR (0.46) | PMP22NOS2NOS3NOS1CA12 | |
| SCHEMBL27872537 | 0.83 | GSR (0.46) | PMP22NOS2NOS3NOS1CA12 | |
| SCHEMBL27888803 | 0.83 | PMP22 (0.42) | PMP22NOS2NOS3NOS1CA12 | |
| SCHEMBL27888797 | 0.83 | PMP22 (0.42) | PMP22NOS2NOS3NOS1CA12 | |
| SCHEMBL13584544 | 0.83 | PMP22 (0.40) | PMP22NOS2NOS3NOS1BHMT | |
| SCHEMBL13584541 | 0.83 | PMP22 (0.40) | PMP22NOS2NOS3NOS1BHMT | |
| SCHEMBL27872419 | 0.81 | GSR (0.53) | PMP22NOS2NOS3NOS1GCLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712676-A | Template-fixed peptidomimetics with CCR10 antagonistic activty | POLYPHOR AG | 2012-10-03 | — | — | CN | disclosed |
| WO-2011060832-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |