Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325578 | 0.91 | KDM4A (0.61) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL24327262 | 0.90 | KDM4A (0.60) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL20614499 | 0.90 | KDM4A (0.60) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL24285005 | 0.90 | KDM4A (0.60) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL20989822 | 0.89 | KDM4A (0.58) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL20227509 | 0.89 | KDM4A (0.58) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL22624862 | 0.89 | KDM4A (0.58) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL22954462 | 0.89 | KDM4A (0.58) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL21325577 | 0.88 | KDM4A (0.57) | SMN1; SMN2LMNAGAAKDM4EKDM4A | |
| SCHEMBL20693310 | 0.88 | KDM4A (0.60) | SMN1; SMN2LMNAGAAKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123316-B2 | Imaging composition and uses thereof | THE UNIVERSITY OF MELBOURNE (AU) | 2021-09-21 | — | — | US | disclosed |
| US-20200246286-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | THE UNIVERSITY OF MELBOURNE (AU) | 2020-08-06 | — | — | US | disclosed |
| US-10653649-B2 | Imaging composition and uses thereof | THE UNIVERSITY OF MELBOURNE (AU) | 2020-05-19 | — | — | US | disclosed |
| EP-3543226-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | The University of Melbourne (AU) | 2019-09-25 | — | — | EP | disclosed |
| US-10398660-B2 | Imaging composition and uses thereof | THE UNIVERSITY OF MELBOURNE (AU) | 2019-09-03 | — | — | US | disclosed |
| EP-3207027-B1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | UNIV MELBOURNE (AU) | 2019-06-19 | — | — | EP | disclosed |
| US-20190099392-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | THE UNIVERSITY OF MELBOURNE (AU) | 2019-04-04 | — | — | US | disclosed |
| US-9980930-B2 | Imaging composition and uses thereof | THE UNIVERSITY OF MELBOURNE (AU) | 2018-05-29 | — | — | US | disclosed |
| US-20170326084-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | THE UNIVERSITY OF MELBOURNE (AU) | 2017-11-16 | — | — | US | disclosed |
| WO-2016058056-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | THE UNIVERSITY OF MELBOURNE (AU) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200246286-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | CA13, CA14, CA12 | SMN1; SMN2 3136/4885LMNA 2199/4885GAA 574/4885 |
| US-10653649-B2 | Imaging composition and uses thereof | CA13, CA14, CA12 | SMN1; SMN2 2660/4885LMNA 1601/4885GAA 673/4885 |
| US-10398660-B2 | Imaging composition and uses thereof | CA13, CA14, CA12 | SMN1; SMN2 2845/4885LMNA 1292/4885GAA 777/4885 |
| US-20170326084-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | CA13, CA14, CA12 | SMN1; SMN2 3136/4885LMNA 2199/4885GAA 574/4885 |
| US-20190099392-A1 | NOVEL IMAGING COMPOSITION AND USES THEREOF | CA13, CA14, CA12 | SMN1; SMN2 3136/4885LMNA 2199/4885GAA 574/4885 |
| US-11123316-B2 | Imaging composition and uses thereof | CA13, CA14, CA12 | SMN1; SMN2 2660/4885LMNA 1601/4885GAA 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.