⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538923 | 0.84 | — | — | |
| SCHEMBL6057149 | 0.77 | — | — | |
| SCHEMBL392675 | 0.77 | — | — | |
| SCHEMBL17472531 | 0.72 | — | — | |
| SCHEMBL723134 | 0.67 | — | — | |
| SCHEMBL22857303 | 0.65 | — | — | |
| SCHEMBL11553111 | 0.65 | — | — | |
| SCHEMBL17702035 | 0.63 | — | — | |
| SCHEMBL722784 | 0.62 | — | — | |
| SCHEMBL386429 | 0.61 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368016-B | Process for producing cyclopentyl alkyl ether compound | 日本瑞翁株式会社 | 2023-09-26 | — | — | CN | disclosed |
| US-20210085625-A1 | CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG | PATHOLOGICA LLC | 2021-03-25 | — | — | US | disclosed |
| EP-3398928-B1 | METHOD FOR PRODUCING CYCLOPENTYL ALKYL ETHER COMPOUND | ZEON CORP (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-10881626-B2 | Controlled release oral pharmaceutical dosage forms comprising MGBG | PATHOLOGICA LLC (US) | 2021-01-05 | — | — | US | disclosed |
| CN-111732499-A | Process for producing cycloalkylalkyl ether compound | 日本瑞翁株式会社 | 2020-10-02 | — | — | CN | disclosed |
| US-20190224144-A1 | METHOD OF TREATMENT WITH ANTI-INFLAMMATORY AND ANALGESIC COMPOUNDS WHICH ARE GI-, RENAL-, AND PLATELET-SPARING | PATHOLOGICA LLC | 2019-07-25 | — | — | US | disclosed |
| US-10350178-B2 | Methods and compositions for treatment of demyelinating diseases | PATHOLOGICA LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-10292950-B2 | Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing | PATHOLOGICA LLC (US) | 2019-05-21 | — | — | US | disclosed |
| US-20180369170-A1 | METHOD OF TREATMENT WITH ANTI-INFLAMMATORY AND ANALGESIC COMPOUNDS WHICH ARE GI-, RENAL-, AND PLATELET-SPARING | PATHOLOGICA LLC | 2018-12-27 | — | — | US | disclosed |
| US-20180360783-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DEMYELINATING DISEASES | PATHOLOGICA LLC | 2018-12-20 | — | — | US | disclosed |
| US-20140187643-A1 | Method of Treatment with Anti-Inflammatory and Analgesic Compounds Which are GI-, Renal-, and Platelet-Sparing | PATHOLOGICA LLC (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140051765-A1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2014-02-20 | — | — | US | disclosed |
| US-8609734-B2 | Methods of treating pain with MGBG | Pathdogica, LLC (US) | 2013-12-17 | — | — | US | disclosed |
| EP-2665471-A2 | CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG | Pathologica, LLC. (US) | 2013-11-27 | — | — | EP | disclosed |
| US-20120289604-A1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120269891-A1 | CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG | PATHOLOGICA LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8258186-B2 | Pharmaceutical for oral delivery comprising MGBG | PATHOLOGICA, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| WO-2012100043-A2 | CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG | Pathlogica LLC (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20110112199-A1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2011-05-12 | — | — | US | disclosed |
| CN-1195988-A | Immunosuppressant | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-10-14 | — | — | CN | disclosed |