Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 7/20 | 0.41 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16307092 | 1.00 | PPARA (0.46) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL16294896 | 1.00 | PPARA (0.46) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL7406075 | 0.89 | PPARA (0.47) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL2206996 | 0.89 | PPARA (0.47) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL3753534 | 0.89 | IL6ST (0.45) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL3753536 | 0.89 | IL6ST (0.45) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL7808720 | 0.88 | PPARA (0.47) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL21435764 | 0.88 | PPARA (0.44) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL21435819 | 0.88 | PPARA (0.44) | PPARALTB4RLTB4R2IDH1IL6ST | |
| SCHEMBL3856583 | 0.88 | PPARA (0.44) | PPARALTB4RLTB4R2IDH1IL6ST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657006-B2 | Macrocyclic factor VIIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-23 | — | — | US | disclosed |
| US-20160115159-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115159-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS | F7, F12, F5 | PPARA 3379/4885LTB4R 1515/4885LTB4R2 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.