Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706424 | 0.93 | NPC1 (0.41) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17706460 | 0.88 | NPC1 (0.49) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17706421 | 0.80 | NPC1 (0.40) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17131207 | 0.80 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL30980128 | 0.79 | NPC1 (0.39) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17131205 | 0.78 | NPC1 (0.49) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17706491 | 0.76 | NPC1 (0.47) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17706469 | 0.76 | NPC1 (0.47) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17706489 | 0.76 | NPC1 (0.47) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL531182 | 0.76 | MEN1 (0.37) | NPC1RAB9AHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160118637-A1 | POWER STORAGE DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) | 2016-04-28 | — | — | US | disclosed |