Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 8/20 | 0.34 |
| ▸ | CD81 | P60033 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17705183 | 1.00 | LSS (0.34) | LSSCD81CNR2 | |
| SCHEMBL310618 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL10629087 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL15164669 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL14518213 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL11001883 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL9650230 | 0.83 | LSS (0.35) | LSSCNR2 | |
| SCHEMBL11342582 | 0.81 | LSS (0.34) | LSSCNR2 | |
| SCHEMBL18165688 | 0.81 | LSS (0.34) | LSSCNR2 | |
| SCHEMBL11739938 | 0.81 | LSS (0.34) | LSSCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321713-B2 | Hyperforin analogs, methods of synthesis, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-04-26 | — | — | US | disclosed |