Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.51 |
| ▸ | KDM4A | O75164 | 3/20 | 0.51 |
| ▸ | KDM5A | P29375 | 6/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19614555 | 0.86 | KDM4C (0.57) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL17710643 | 0.85 | KDM4C (0.47) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL17710625 | 0.85 | KDM4C (0.55) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL16075664 | 0.84 | KDM2B (0.69) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL16075683 | 0.83 | KDM2B (0.60) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL20978933 | 0.83 | KDM2B (0.60) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL16075667 | 0.83 | KDM2B (0.60) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL17710642 | 0.81 | KDM2B (0.65) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL16075663 | 0.81 | KDM4C (0.74) | KDM4CKDM2BKDM4AKDM5AKDM5B | |
| SCHEMBL20978902 | 0.79 | KDM2B (0.63) | KDM4CKDM2BKDM4AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9527829-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20160122314-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122314-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM3B | KDM4C 13/4885KDM2B 19/4885KDM4A 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.