Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | TST | Q16762 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253594 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4810276 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9579598 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9154487 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8496560 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8702332 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8081798 | 0.98 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8053812 | 0.94 | HSD17B10 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8535115 | 0.94 | HSD17B10 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10986143 | 0.91 | RARB (0.58) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938003-B | Preparation method of fingolimod hydrochloride | 新发药业有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-11046646-B2 | Alkylphenyl compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-06-29 | — | — | US | disclosed |
| US-20210147357-A1 | ALKYLPHENYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| CN-110938003-A | Preparation method of fingolimod hydrochloride | 新发药业有限公司 | 2020-03-31 | — | — | CN | disclosed |
| WO-2019032632-A1 | ALKYLPHENYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |
| EP-3092222-B1 | IMPROVED FINGOLIMOD PROCESS | EMCURE PHARMACEUTICALS LTD (IN) | 2018-02-14 | — | — | EP | disclosed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-3092222-A1 | IMPROVED FINGOLIMOD PROCESS | Emcure Pharmaceuticals Limited (IN) | 2016-11-16 | — | — | EP | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-6159910-A | Aluminum nitride composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0957145-A2 | Rust prevention | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0615562-B1 | WATER REPELLENT ARAMIDS | DU PONT (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0225602-B1 | ALPHA-HYDROXYTHIO ETHERS | CIBA-GEIGY AG (CH) | 1991-10-09 | — | — | EP | disclosed |
| US-4808572-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0123543-B1 | LEUKOTRIENE ANTAGONISTS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM | MERCK FROSST CANADA INC. (CA) | 1988-02-03 | — | — | EP | disclosed |
| EP-0225602-A2 | Alpha-hydroxythio ethers | CIBA-GEIGY AG (CH) | 1987-06-16 | — | — | EP | disclosed |
| US-4609744-A | 4-oxo-benzopyran carboxylic acids | MERCK FROSST CANADA INC. (CA) | 1986-09-02 | — | — | US | disclosed |
| EP-0123543-A1 | Leukotriene antagonists, their production and use and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-10-31 | — | — | EP | disclosed |
| US-4405810-A | ANTIALLERGENS, BRONCHODILATORS | SCHERING CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | ESR1 1797/4885ADRA2A 280/4885ADORA3 305/4885 |
| US-20210147357-A1 | ALKYLPHENYL COMPOUNDS | LPAR1, PLA2R1, LPAR3 | ESR1 1460/4885ADRA2A 554/4885ADORA3 1423/4885 |
| US-11046646-B2 | Alkylphenyl compounds | S1PR1, S1PR3, S1PR2 | ESR1 1904/4885ADRA2A 200/4885ADORA3 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.