Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 4/20 | 0.57 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.57 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.57 |
| ▸ | AEBP2 | Q6ZN18 | 4/20 | 0.57 |
| ▸ | EZH2 | Q15910 | 19/20 | 0.55 |
| ▸ | EZH1 | Q92800 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467772 | 0.75 | EZH2 (0.63) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL18496646 | 0.75 | EED (0.55) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL20614030 | 0.74 | EZH2 (0.64) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15391062 | 0.74 | EED (0.78) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL16899334 | 0.74 | EED (0.58) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL2587195 | 0.74 | EZH2 (0.58) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15391060 | 0.73 | EED (1.00) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19621000 | 0.72 | EZH2 (0.54) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL12180132 | 0.72 | EZH2 (0.54) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL16360815 | 0.72 | EZH2 (0.54) | EEDRBBP4SUZ12AEBP2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212639-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016066697-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-06 | — | — | WO | disclosed |