SCHEMBL177146

SCHEMBL177146

C[CH][Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054074 0.67
SCHEMBL9692437 0.67
SCHEMBL6054013 0.67
SCHEMBL6334952 0.67
SCHEMBL336082 0.64
SCHEMBL336081 0.64
SCHEMBL8996349 0.64
SCHEMBL9025457 0.62
SCHEMBL3886042 0.62
SCHEMBL175598 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3834 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140934-A1 PREPARATION METHOD FOR LINKER-DRUG CONJUGATE AND INTERMEDIATE THEREOF 上海复旦张江生物医药股份有限公司 2024-07-04 WO claimed
CN-118221644-A Pyrrolidine derivative, composition and application thereof 上海京新生物医药有限公司 2024-06-21 CN claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
WO-2024089310-A1 BIODEGRADABLE IMINOSUGARS AND AMINO CYCLITOL GLYCOSIDES INHIBITING ALPHA-GLUCOSIDASE WITH SYNERGISTIC INSECTICIDE OR ACARICIDE ACTIVITY OR BOTH FRANCISCO ARAGÓN S.L.U (ES) 2024-05-02 WO claimed
US-11932666-B2 Polymerizable compound, compound, and method for producing boranophosphate oligomer TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2024-03-19 US claimed
CN-117384177-A Synthesis method of chiral pyrrole bridged ring compound 北京化工大学 2024-01-12 CN claimed
US-20230250200-A1 IMPROVED CATALYSTS FOR INTERMOLECULAR CYCLOADDITION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-10 US claimed
CN-116217655-A Preparation method of intermediate of linker drug conjugate 上海复旦张江生物医药股份有限公司 2023-06-06 CN claimed
CN-116217654-A Preparation method of linker drug conjugate and intermediate thereof 上海复旦张江生物医药股份有限公司 2023-06-06 CN claimed
CN-116178386-A Preparation method of linker drug conjugate and intermediate thereof 上海复旦张江生物医药股份有限公司 2023-05-30 CN claimed
EP-0154581-B1 ALPHA-CHLORINATED CARBONATES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION TO THE PROTECTION OF AMINIC FUNCTIONS IN AMINO ACIDS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1988-06-08 EP claimed
EP-0268963-A1 Benzazolylthio-carbapenem antibiotics BAYER AG (DE) 1988-06-01 EP claimed
US-4725680-A AMINATION, CLEAVAGE, NEUTRALIZATION SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1988-02-16 US claimed
EP-0247431-A1 Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use BAYER AG (DE) 1987-12-02 EP claimed
EP-0154904-B1 ACYLAMINO OXO OR HYDROXY SUBSTITUTED ALKYLAMINO THIAZINES AND THIAZEPINES E.R. Squibb &amp; Sons, Inc. (US) 1987-10-28 EP claimed
US-4652665-A BLOCK AMINE FUNCTION OF AMINO ACIDS; PEPTIDE SYNTHESIS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1987-03-24 US claimed
US-4636229-A FUMARIC DIESTER POLYMER NIPPON OIL COMPANY, LIMITED (JP) 1987-01-13 US claimed
EP-0195963-A1 Process for the preparation of carbapenem intermediates BAYER AG (DE) 1986-10-01 EP claimed
EP-0154904-A1 Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines E.R. Squibb &amp; Sons, Inc. (US) 1985-09-18 EP claimed
US-4512988-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-04-23 US claimed