SCHEMBL17716633

SCHEMBL17716633

CCOC(=O)CCC1(CCC(=O)OCC)C(=O)N(c2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.53
CYP2C19 P33261 1/20 0.46
GAA P10253 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
PDE4D Q08499 1/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17716275 0.95 ELANE (0.48) ELANECYP2C19GAAALDH1A1TP53
SCHEMBL17716644 0.86 ELANE (0.46) ELANECYP2C19GAAALDH1A1TP53
SCHEMBL19184838 0.83 CYP2C19 (0.47) ELANECYP2C19GAAALDH1A1TP53
SCHEMBL17716271 0.82 GAA (0.42) ELANECYP2C19GAAALDH1A1TP53
SCHEMBL19184841 0.78 GAA (0.43) ELANECYP2C19GAAALDH1A1TP53
Hydrochloric Acid SCHEMBL8813046 0.76 MAPK1 (0.66) ELANECYP2C19GAAALDH1A1L3MBTL1
SCHEMBL17716273 0.76 ELANE (0.89) ELANE
SCHEMBL17716637 0.74 ELANE (0.54) ELANECYP2C19GAAALDH1A1TP53
SCHEMBL17716638 0.73 ELANE (0.51) ELANECYP2C19ALDH1A1KMT2AL3MBTL1
SCHEMBL10009363 0.71 APEX1 (0.60) GAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9718933-B2 Optical film, and polarizing plate and liquid crystal display device employing same FUJIFILM CORPORATION (JP) 2017-08-01 US disclosed
US-20160122486-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed