SCHEMBL17718878

SCHEMBL17718878

Clc1ccccc1-c1nc2ccc(-c3ccccc3)cn2c1CN1CCOCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 17/20 1.00
▸ SLC2A3 P11169 1/20 0.63
▸ SLC2A4 P14672 1/20 0.63
▸ SLC2A2 P11168 1/20 0.62
▸ SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718927 0.90 SLC2A1 (0.82) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL17718873 0.88 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2SMN1; SMN2
SCHEMBL16246716 0.87 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL17718885 0.86 SLC2A1 (0.79) SLC2A1SLC2A3SLC2A4
SCHEMBL17718969 0.86 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2SMN1; SMN2
SCHEMBL17718874 0.85 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SMN1; SMN2
SCHEMBL17718880 0.84 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL17719007 0.84 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL17718848 0.83 SLC2A1 (0.89) SLC2A1SLC2A3SLC2A4SLC2A2SMN1; SMN2
SCHEMBL17718919 0.83 SLC2A1 (1.00) SLC2A1SLC2A3SLC2A4SLC2A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS SLCO1A2, SLCO2B1, SLCO2A1 SLC2A1 6/4885SLC2A3 13/4885SLC2A4 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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