SCHEMBL17719081

SCHEMBL17719081

CC(C)(O)C(=O)N1CCN(Cc2c(-c3ccc(Cl)cc3Cl)nc3cnc(C4CC4)cn23)CC1

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC2A2 P11168 15/20 0.71
▸ SLC2A1 P11166 3/20 0.55
▸ EPHX2 P34913 1/20 0.45
▸ KCNK3 O14649 1/20 0.45
▸ KCNK9 Q9NPC2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17719031 0.90 SLC2A2 (0.76) SLC2A2SLC2A1
SCHEMBL17719082 0.88 SLC2A2 (0.72) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719072 0.86 SLC2A2 (0.70) SLC2A2SLC2A1EPHX2
SCHEMBL17719058 0.85 SLC2A2 (0.68) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719035 0.84 SLC2A2 (0.67) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719064 0.84 SLC2A2 (0.67) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719056 0.84 SLC2A2 (0.67) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719090 0.83 SLC2A2 (1.00) SLC2A2SLC2A1KCNK3KCNK9
SCHEMBL17719120 0.78 SLC2A2 (1.00) SLC2A2SLC2A1
SCHEMBL17719137 0.78 SLC2A2 (1.00) SLC2A2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS SLCO1A2, SLCO2B1, SLCO2A1 SLC2A2 8/4885SLC2A1 6/4885EPHX2 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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