Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722086 | 0.91 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722276 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722034 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722049 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722272 | 0.89 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722180 | 0.89 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722084 | 0.88 | SCN9A (1.00) | SCN9AKCNH2SCN5A | |
| SCHEMBL17722283 | 0.88 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722147 | 0.88 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722260 | 0.88 | SCN9A (0.94) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334269-B2 | Carboxamides as inhibitors of voltage-gated sodium channels | AMGEN INC. (US) | 2016-05-10 | — | — | US | claimed |