Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300474 | 0.96 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722102 | 0.88 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722103 | 0.88 | SCN9A (1.00) | SCN9A | |
| SCHEMBL2355857 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL2358000 | 0.86 | SCN9A (1.00) | SCN9A | |
| SCHEMBL2355618 | 0.85 | SCN9A (0.82) | SCN9A | |
| SCHEMBL17722057 | 0.81 | SCN9A (1.00) | SCN9A | |
| SCHEMBL2301301 | 0.81 | SCN9A (0.91) | SCN9A | |
| SCHEMBL17722117 | 0.80 | SCN9A (1.00) | SCN9A | |
| SCHEMBL2357684 | 0.80 | SCN9A (1.00) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334269-B2 | Carboxamides as inhibitors of voltage-gated sodium channels | AMGEN INC. (US) | 2016-05-10 | — | — | US | claimed |