Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR1D | P28221 | 5/20 | 0.48 |
| ▸ | HTR1B | P28222 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762208 | 1.00 | TSHR (0.68) | TSHRNR5A1THRAHTR1AHTR1D | |
| SCHEMBL295119 | 1.00 | TSHR (0.68) | TSHRNR5A1THRAHTR1AHTR1D | |
| SCHEMBL24168626 | 0.95 | TSHR (0.59) | TSHRMAPTTP53MAPK1TDP1 | |
| SCHEMBL31413515 | 0.89 | TSHR (0.50) | TSHRMAPTMAPK1TDP1KDM4E | |
| SCHEMBL4945033 | 0.89 | NR5A1 (0.62) | TSHRNR5A1THRATP53CA12 | |
| SCHEMBL10642885 | 0.89 | NR5A1 (0.62) | TSHRNR5A1THRATP53CA12 | |
| SCHEMBL347683 | 0.89 | NR5A1 (0.62) | TSHRNR5A1THRATP53CA12 | |
| SCHEMBL1114857 | 0.87 | MAPT (0.53) | TSHRHTR1AHTR1BMAPTTP53 | |
| SCHEMBL17162145 | 0.85 | NR5A1 (0.58) | TSHRNR5A1THRATP53MAPK1 | |
| SCHEMBL17018215 | 0.85 | NR5A1 (0.58) | TSHRNR5A1THRATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9335442-B1 | Polarizing film and display device including the polarizing film | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-05-10 | — | — | US | disclosed |