Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 7/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.62 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.60 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722506 | 0.97 | TFPI (0.63) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722489 | 0.97 | TFPI (0.63) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722486 | 0.96 | TFPI (0.66) | TFPICXCR4NMUR2NMUR1 | |
| SCHEMBL17722498 | 0.96 | TFPI (0.63) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722507 | 0.95 | TFPI (0.65) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722505 | 0.95 | TFPI (0.62) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722509 | 0.94 | TFPI (0.60) | TFPICXCR4NMUR2NMUR1 | |
| SCHEMBL30788356 | 0.93 | TFPI (0.61) | TFPICXCR4OPRM1OPRK1NMUR2 | |
| SCHEMBL17722508 | 0.93 | TFPI (0.62) | TFPINMUR2NMUR1 | |
| SCHEMBL17722477 | 0.92 | TFPI (0.63) | TFPINMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122383-A1 | Peptide Ligation | THE UNIVERSITY OF SYDNEY (AU) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122383-A1 | Peptide Ligation | PTMS, PTMA, QPCTL | TFPI 3159/4885CXCR4 2876/4885OPRM1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.